George Miklos

George Miklos holds a PhD in genetics and has extensive laboratory experience in molecular biology and biotechnology. He was an invited member of the Human Genome Project carried out by J Craig Venter at CELERA, Rockville, MD, USA and has advised firms including Novartis AG, Basel, Switzerland, and Fabric Genomics Inc, Oakland, CA, USA on translating genomic data into actionable information for clinicians. He was instrumental in setting up two Australian biotechnology companies, Genetic Signatures (ASX:GSS) and Regeneus (ASX:RGS), both of which had successful IPOs. He is an inventor on multiple granted patents on epigenomic detection systems in microrganisms, human diseases and clinical radiotherapy.

He founded Atomic Oncology, a private firm aimed at translating a unique application of an atomic technology, Radnos, into practical patient-centric information for medical oncologists and radiation oncologists. The technology leverages the universality of radiation action, and can be utilized in conjunction with any current form of radiation treatment, be that using external beam radiation therapy, brachytherapy or more specialized instrumentation such as GammaKnife and Proton Beam.

Publications

PARP inhibitors in ovarian cancer

New England Journal of Medicine, 2020 April 16: 382(16):1573. doi: 10.1056/NEJMc2000644. Ian E Haines and George L Gabor Miklos

Bevacizumab moonshots: an important outcome from the latest ovarian cancer mission

Journal of Clinical Oncology, 2020 Jan 10;38(2):171-172. doi: 10.1200/JCO.19.01912 Haines I E and Gabor Miklos G L

Distributions of manganese in diverse human cancers provides insights into tumour radioresistance

Metallomics. 2018. doi:10.1039/c8mt00110c. Philip Doble and George L Gabor Miklos

Latest data on prostate cancer treatment: jaw dropping and clearcut

Medical Journal of Australia InSight. 2017. Issue 29, 31 July. Ian Haines and George L Gabor Miklos

Screening for prostate cancer: time to put all the data on the table

British Medical Journal. 2016. Ian Haines, Richard J Ablin and George L Gabor Miklos

Prostate Cancer Screening in Europe

The Lancet.  2015. Ian Haines, Richard J Ablin and George L Gabor Miklos

Psa Screening, lives saved, and hormonal monotherapy: it’s time to face some quietly ignored facts

2014.  Uro Today. I E Haines and George L Gabor Miklos

Bevacizumab for newly diagnosed glioblastoma

New England Journal of Medicine, 370, 2048 Ian E Haines and George L Gabor Miklos

Prostate-specific antigen screening trials and prostate cancer deaths: the androgen deprivation connection

Journal of the National Cancer Institute. 2013. Ian E. Haines, George L. Gabor Miklos

The dilemmas of prostate cancer screening 

2013 Medical Journal of Australia, 199(9) 582.George L. Gabor Miklos

Time to mandate data release and independent audits for all clinical trials 

2011, Medical Journal of Australia, 195, (10), 575-577 Ian E Haines and George L Gabor Miklos

Bevacizumab in neoadjuvant treatment for breast cancer

New England Journal of Medicine, 366, 1638. George L Gabor Miklos

Bullet-train biotech & reality 

2011, Genetic Engineering and Biotechnology News, 1 Jan (Vol. 31. No.1). George L. Gabor Miklos

Paclitaxel plus bevacizumab for metastatic breast cancer 

2008, New England Journal of Medicine, 358, 1637. Ian E. Haines and George L. Gabor Miklos

The human cancer genome project - one more misstep in the war on cancer

2005, Nature Biotechnology, 23, 535 - 537. George L Gabor Miklos.

Microarray reality checks in the context of a complex disease 

2004, Nature Biotechnology, 22, 615-621. George L Gabor Miklos and Ryszard Maleszka

A comparison of whole-genome shotgun-derived sequencing of mouse chromosome 16 and the human genome 

2002, Science, 296, 1661-1671 R J Mural, M D Adams, E W Myers, H O Smith, George L Gabor Miklos, et al.,

The sequence of the human genome 

2001, Science, 291,1304-1351 J.Craig.Venter., Adams, M.D., Myers, G., Li, P., Mural, R.J., Sutton, G., Smith, H.O., Yandell, M., Evans, C.A., Holt, R.A. Gocayne, J.D., Amanatides, P., Ballew, R.M., Huson, D.H., Wortman, J.R., Zhang, Q., Kodira, C., Zheng, X., Chen, L., Skupski, M., Subramanian, G., Thomas, P.D., Zhang, J., George L. Gabor Miklos, et al.,.

Integrating molecular medicine with functional proteomics: expectations and realities 

2001, Proteomics, 1, 30-41. George L Gabor Miklos and Ryszard Maleszka

Protein functions and biological contexts 

2001, Proteomics, 1, 169-178. George L Gabor Miklos and Ryszard Maleszka

The genome sequence of drosophila melanogaster 

2000, Science, 287, 2185-2195 Adams, M.D., Celniker, S. E., Holt, R.A., Evans, C. A., Gocayne, J.D., Amanatides, P.G., Scherer, S.E., Li, P.W., Hoskins, R.A., Galle, R.F., George, R.A., Lewis, S.E., Richards, S., Ashburner, M., Henderson, S.N., Sutton, G.G., Wortman, J.R., Yandell, M.D., Zhang, Q., Chen, L.X., Brandon, R., Rogers, Y.-H., C., Blazej, R.G., Champe, M., Pfeiffer, B.D., Wan, K.H., Doyle, C., Baxter, E.G., Helt, G., Nelson, C.R., George L Gabor Miklos, et al.,

Comparative genomics of the eukaryotes 2000

Science, 287, 2204-2215. Rubin, G. M., Yandell, M. D., Wortman, J. R., George L Gabor Miklos, et al.,

Deus ex genomix 

2000, Nature Neuroscience, 3, 424-425. George L Gabor Miklos and Ryszard Maleszka